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Between 1994 and 2004, Oxalosuccinic acid capacity exclusively for patients with Down syndrome; others serve as tertiary referrals centers, situated selleck compound most commonly in divisions of genetics, developmental�Cbehavioral pediatrics, neurodevelopmental disabilities or neurology. Since 1967, the Down Syndrome Program at Boston Children's Hospital has offered weekly, multidisciplinary evaluations of children with DS under the age of 3. Serving as a tertiary referral-based clinic, the Program is positioned within the Developmental Medicine Center in the Department of Medicine. Beginning in 2009, the Program expanded its services to include a separate weekly, multidisciplinary evaluation of children with DS between the ages of 3 and adulthood. This new clinic includes a visit with a physician who specializes in Down syndrome (developmental�Cbehavioral pediatrician and/or medical geneticist), a nutritionist, an audiologist, resource Ponatinib ic50 specialists, and, when needed and available, other healthcare professionals. Prior to their clinical visit, parents and/or guardians are asked to complete a comprehensive intake questionnaire, which includes information about pre-existing conditions, previous laboratory and radiological studies, and a series of questions about the patient's sleep habits. (Intake available at www.childrenshospital.org/downsyndrome.) The opening of our new clinic in 2009 afforded an opportunity to ask: What new diagnoses, if any, were identified in our patients with DS as a result of their visit to our clinic? How many of our new patients were up-to-date on the recommended DS healthcare screenings? And, ultimately, what value does a DS specialty clinic bring to people with DS and their families? We analyzed the records of all patients with DS, ages 3 and older, presenting for a new patient visit during the inaugural year of our new clinic (October 3, 2009�COctober 3, 2010).