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Positive predictive value (PPV) and negative predictive value (NPV) of self-reported history of chickenpox were estimated using the following ratio: PPV=Women?positive?for?both?disease?and?testswomen?with?disease AG-014699 mouse NPV?=?Women?negative?for?both?disease?and?testswomen?with?disease RESULTS Out of 250 young women in the study, 178 (71.2%) were diagnosed as antibody-positive and the rest (72 participants 28.8%) as antibody-negative against VZV. The maximum and minimum antibody levels were obtained 0.06 and 940.93 IU/mL, respectively. The mean level of individuals�� antibody was 37.05 IU/mL. No borderline (equivocal) antibody level was observed; hence any need to rerun the test. The age of participants ranged from 13 to 40 years with the mean of 22.39 (�� 5.4, standard deviation). The association between antibody titer and age of participants was statistically significant (Spearman correlation ��=0.29, PProtein Tyrosine Kinase inhibitor (years). Bars represent 95% confidence intervals. In comparison of seroprevalence between women living in rural area with those living in urban areas, there was not any significant difference (Chi-squared, P = 0.56). Moreover, no statistically significant association between the level of immunity against VZV and participants�� occupation (Fisher exact test, P = 0.987) and education (Chi-squared, P = 0.295) Quetiapine were observed. Table 1 reports the seroprevalence of antibodies against VZV with respect to the number of siblings. As the number of sisters and brothers increased, a tendency toward more positive and less negative outcomes can be seen. In families with more than eight siblings, 83.3% of women showed positive test results. The Fisher exact test indicated a significant association between the immunity level of participants to VZV and their family sizes (P = 0.03). Table 1. The prevalence of antibodies to varicella-zoster virus according to the number of siblings Subjects were also asked about their history of chickenpox (Table 2). The total number of 111 individuals found with positive chickenpox history and 134 reported negative history. Table 2.