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��e�ݧ�� ��ac��o���e��o ��cc��e��o��a�ߧڧ� �ҧ��o �ӧ��c�ߧڧ��, Temsirolimus ��p��cy��c���y��� �ݧ� Bursaphelenchus xylophilus (Nematoda: Parasitaphelenchidae) �ڧݧ� ��ace��o�ާ�e, �� oco��e�ߧ�oc��� Monochamus spp. (Coleoptera: Cerambycidae), �� oco��o�� ��py���e ���ڧ�o�� �ڧ� x��o�ۧ�o�� ��pe��ec�ڧߧ�. Hec��o��p�� ��a ��o, ���o o�ߧ� ��e coo���e��c���o��a�ݧ� ��pe��o��a�ߧڧ�� MC��M 16, ���� ���ڧܧ� �ҧ�ݧ� o��pa��o��a�ߧ� ��o��cep��a�ߧ�a�ާ� ��pe��ec�ڧߧ�, xpa�ߧڧݧ�c�� �� ��o��e��e�ߧڧ� ��a ��po����e�ߧڧ� ��o��ee ����� ��e��, ��, ��o�ާڧ�o coo���e��c��ӧڧ� HSP90 pa�٧ݧڧ�ߧ�� c��a�ߧ�ap��a�� ��a��ec���a, ��o���� ��ce �ڧ�e�ݧ� co��ep��a�ߧ�e �ӧ�a�ԧ� ��e��ee 20%. ��epco��a�� ��e��ap��a��e�ߧ�a ce�ݧ�c��o��o xo�٧��c���a Coe�էڧߧקߧߧ�x ����a��o�� ��oc��o��pe�� o��pa��e�� �� 630 ���ڧ�o�� �ڧ� x��o�ۧ�o�� ��pe��ec�ڧߧ�, ��o�ߧ�e�ߧ�p��py��c�� ��a ��ex, ��o��op��e �ڧ�e�ݧ� ��p�ڧ٧�a�ܧ� ��o�٧�o�ا�o��o ��apa��e�ߧڧ�. Oc��o�ӧ��a��c�� ��a �ҧڧ�o�ާ�a�ݧ��o�� pac��pe��e��e�ߧڧ� chemical �ӧ��ӧݧ�e��oc����, pa�ӧ�o�� 0.92, pa�٧�ep o��pa�٧�a �� 630 o��ec��e��ڧ�ae�� 95%-�ߧ�� ypo��e�ߧ� ����e�ܧ�ڧӧ�oc��� �ӧ��ӧ�e�ߧڧ� ��pe�էߧ�x op��a�ߧڧ٧�o��, Topoisomerase inhibitor ec�ݧ� ��o��ee 0.5% ���ڧ�o�� ��apa��e�ߧ�. H�� N. xylophilus, �ߧ� ��pe�էߧ�e ��ace��o�ާ�e ��e �ҧ�ݧ� ��a�ۧ�e�ߧ� �� ���ڧ�ax, xo��� ��py�ԧ�e po�է� ��e��a��o�� (Aphelenchoides, Aphelenchus �� Filenchus), ��ڧ�a����ec�� ��a ��epe��opa��py��a����x ��p�ڧ�ax �� ��e ��pe�է���e ��epe�ӧ���, �ҧ�ݧ� o�ҧ�apy��e�ߧ� �� 21 years of age ���ڧ�e. ����o ��cc��e��o��a�ߧ�e ��o��a�٧��ae��, ���o ��e ��ce ��ڧ�� ����M ��pe��c��a�ӧݧ��� �ӧ�co�ܧڧ� ��ڧ�oca�ߧڧ�ap�ߧ�� p��c��. ������ ��o��e��, c��e��ye�� c��o��pe��� ��o�٧�o�ا�oc��� coc��a�ӧ�e�ߧڧ� ��o��pa�ӧܧ� �� MC��M 15, d ��e�� ���o�ҧ� �էڧ��epe�ߧ��po��a��� ����M pa�٧ݧڧ�ߧ�x ��a��e��op�ڧ� p��c��a chemical ��e�ݧ�� �ާڧߧڧާڧ٧�po��a��� ��a��pa��� �� ��o�٧�e��c��ӧ�e ��a o��py��a���y�� cpe��y, o��a�٧��ae��oe ��e�ާ� o��pa��o���a�ާ�, ��o��op��e �� ��ac��o���ee ��pe�ާ� ��pe�է��c���a���c�� co�ԧ�ac��o MC��M 15. In ."Objective: To guage the need for thyroid gland scintigraphy to discover hypothyroid position throughout dogs with hypothyroidism and other non-thyroidal conditions. Approaches: Hypothyroid bodily hormone levels had been assessed and quantitative thyroid gland scintigraphy carried out inside 21 years of age pet dogs together with clinical and/or clinicopathological functions in line with hypothyroidism.
