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0002, P?buy Cabozantinib of the filters were counted. Invasion of control cells was set at 100%. The data expressed as mean?��?SEM; P?tuclazepam 2A). Ovarian cancer cells (OVCAR-3, A2780/CP70) treated with fibronectin (10??g/mL) had increased phosphorylation of FAK; P?Tofacitinib order cancer cells, Figure 2B). Western blotting was assessed by densitometric analysis using NIH Image J software (NIH Image, Bethesda, MD, USA). We examined whether inhibition of FAK had any effects on FAK phosphorylation, migration and invasive response in ovarian cancer cells. Knockdown of FAK expression with siRNA inhibited P-FAK (Figure 3A). The inhibitory siRNA also reduced enhancement of migration and invasion in both types of ovarian cancer cells (OVCAR-3, A2780/CP70), compared with untreated cells (P?