Cannabis Study: Full-Spectrum Cannabis Extracts Much more Medically Effective than CBD Alone

Cannabidiol (CBD) has been the concentrate of many medical cannabis research, and continues to prove itself as a potent anti-inflammatory drug. What makes CBD even more desirable for some patients is that it does not trigger the psychoactive effects related with tetrahydrocannabinol (THC).

An very fascinating study (Overcoming the Bell-Shaped Dose-Response of Cannabidiol by utilizing Cannabis Extract Enriched in Cannabidiol) was just published out of the Lautenberg Center for General and Tumor Immunology in Jerusalem. The study examines the effectiveness of administering isolated cannabinoid extracts (a CBD-only formula) versus whole plant extracts (which include the full variety of the plant’s cannabinoid content).

The Hadassah Medical School at the Hebrew University of Jerusalem sought to compare the effectiveness of a totally purified CBD extract versus a full-spectrum extract of cannabis flowers containing large quantities of CBD. The conclusion of the study was that the entire plant extract, which contained a large percentage of CBD but also contained traces of the other cannabinoids, proved far much more effective than CBD-only options in alleviating inflammation and pain sensation. The study demonstrated that a whole plant extract, containing the entire range of cannabinoids present in raw cannabis, will continue to offer relief for inflammation as the dose is increased. When supplied as an isolated cannabinoid extract, CBD on its personal yielded a bell-curve of effectiveness, which is not desirable for medical remedies seeking efficient relief that corresponds with the dosage.

Outcomes Of CBD vs. Full-Spectrum on Inflammation and Pain

The data graphs beneath evaluate isolated cannabidiol (CBD) against a full-spectrum cannabis extract (from a CBD-rich strain). In all of the tests, the isolated CBD was ineffective both before and following a certain dosage, while the effectiveness of the full-spectrum answer continued to increase as greater doses were administered. The outcomes all indicate that CBD is only efficient against swelling and pain at a particular dose, and that cannabis options containing a full range of cannabinoids will continue to offer corresponding effects as the dosage is elevated.

Injections: The isolated CBD injection was moderately effective at 5 mg/kg, but became much less effective when the dose was higher. The shape of the graph resembles a bell-curve, indicating that the CBD-only formula lost effectiveness after a certain dose. The outcomes from the cannabis flower extract showed that the synergy in between the cannabinoids yielded greater relief as the dosage was increased, which is desirable in medicine.

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