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001) and causes blindness (pNatural Product Library datasheet and smoking status among students who had seen a cigarette ... Cognitive processing of warnings Among students who had seen a cigarette pack in GDC-0973 molecular weight the previous 6?months, there was no significant change in the cognitive processing items between 2011 and 2013 (table 5). While there was some difference in these items by smoking status, there was no significant interaction between survey year and smoking status (table 5). Table?5 For students who had seen a cigarette pack in past 6?months, mean frequency of reading, attending to, thinking about and talking about health warnings and for students with smoking experience, the frequency of not having a cigarette or thinking ... Among ES and CS, there was no significant change in the frequency of not having a cigarette because of the health warnings (p=0.52). Among students who had smoked in the previous 12?months, there was no significant change in the frequency of thinking about quitting (p=0.28). There was no interaction between year and smoking status for either item (table 5). Discussion With around 60% of students surveyed seeing cigarette packs in the preceding 6?months, GHWs on tobacco packs have the potential to reach a large proportion of adolescents. Our study found the introduction of the new cigarette packaging in late 2012 did not have an immediate impact on the cognitive processing of GHW among adolescents who had seen a cigarette pack in the previous 6?months. However, we Aldosterone found a significant increase in the proportion of these adolescents agreeing that smoking causes bladder cancer, a cancer included in the only completely new health warning introduced with the new cigarette packaging. This increase is notable given that the warning only started appearing on significant numbers of packs quite late in our survey period. We have shown previously that 6?months after the introduction of GHWs in 2006, adolescents�� cognitive processing of warnings had increased from pre-GHW levels.6 However, we have also found that this increase dissipated after 5?years of exposure, with cognitive processing levels in 2011 similar to pre-GHW levels.