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This type of neuron is defined as SL type. On the other hand, the neuron in Figure?Figure7B7B exhibited greater D2 activity in LS trials than in SL trials, and is defined as LS type. The activity of these neurons changed according to the trial type, but Adenylyl cyclase did not change within the same type of trials even if the C2 duration was altered. Figure 7 D2 response neurons representing the order of relative cue duration. (A) An example of an SL type of D2 response neuron. Top; The raster diagram, which is aligned with the D2 onset and rearranged by the C2 duration, is displayed separately for SL and ... Some D2 response neurons changed their activity depending on the C2 duration. Figure?Figure88 demonstrates two examples of neurons exhibiting C2-dependent D2 activity. The neuron shown in Figure?Figure8A8A exhibited phasic activity during the D2 period both in SL and LS trials. The magnitude of the D2 activity changed depending on the C2 duration. The activity was greater in trials with a long C2 than in those with a short one. Normalized firing rates during the D2 period were plotted separately for SL and LS trials against the BIBF 1120 nmr C2 duration (Fig.?(Fig.8A8A bottom). Linear regression analyses revealed the dependence of D2 activity on the C2 duration with a positive gradient both in SL trials (a?=?0.79, P?=?0.01) and in LS trials (a?=?0.62, P?=?0.01). The neuron shown in Figure?Figure8B8B also exhibited phasic activity during the D2 period. The activity was greater in trials with a short C2 than in those with a long one. Normalized firing rates during the D2 period were plotted separately for SL and LS trials against the C2 duration (Fig.?(Fig.8B8B bottom). Linear regression analyses revealed the dependence of D2 activity on the C2 duration with a negative gradient both in SL trials (a? = ??0.37, P?buy GS-7340 C2 duration. Top; The raster diagram, which is aligned with the D2 onset and rearranged by the C2 duration, ... On the other hand, the neuron in Figure?Figure99 showed greater D2 activity in LS trials than in SL trials, and the D2 activity changed depending on the C2 duration in LS trials, but not in SL trials. Linear regression analyses revealed the dependence of D2 activity on the C2 duration with a negative gradient (?0.47, P?