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As a result, it is imperative to either apply sunscreen or cover up the exposed body surfaces even when under such shading devices. ""Hypopigmented mycosis fungoides (MF) is an uncommon variant of MF. It is rare in Caucasians but more common in young LMTK2 skin-of-color individuals. To date, there are only a few reports on UV-based treatment for this condition. To analyze the efficacy of PUVA photochemotherapy and narrowband UVB (NBUVB) phototherapy for hypopigmented MF. A retrospective study of nine patients who received PUVA or NBUVB was performed. The clinical response, total number of treatments, cumulative UV doses, disease-free interval and adverse effects were recorded. Eight patients had stage IA and one patient had stage IB. Six patients received NBUVB and three patients received PUVA. Three patients (50%) in the NBUVB group and three patients (100%) in the PUVA group had complete response (CR). Total UV dose to get maximal clinical response ranged from 27.1�C59.6?J/cm2 in the NBUVB group and 244�C669.1?J/cm2 in the PUVA group. In six patients U0126 who had CR, recurrence was found in four (66.7%), and the disease-free interval ranged from 2 months to 6?years. PUVA and NBUVB are effective for hypopigmented MF. Comparing between these two methods, PUVA provided a better response than NBUVB. Although the disease responded well to phototherapy, relapse was common. ""Oral lichen planus is an autoimmune disorder that has posed a challenge in Romidepsin nmr spite of the several treatment modalities available. Here, we have proposed yet another treatment modality, photodynamic therapy, for this condition. The aim of the study was to treat patients having symptomatic oral lichen planus with photodynamic therapy with methylene blue as photosensitizer. Twenty patients with symptomatic oral lichen planus were included in the study. They were treated with 5% methylene blue mediated photodynamic therapy (light source: Xenon arc lamp, wavelength: 630?��?5?nm, total dose: 120?J/cm2 per sitting) in four sessions (1st, 4th, 7th and 15th day). Follow-up was done on second and fourth week after the therapy. There was significant improvement in signs and symptoms of the lesion at first and second follow-up visits (P-value?