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Results Of the 130 participants 98 (75.4%) were males and 32 (24.6%) females. 77 participants (59.23%) reported being single, 25 (19.23%) divorced, 23 (17.7%) married, and 5 (3.8%) widowed. 80 participants (61.5%) reported having no children whereas 50 (38.5%) of them reported having at least one. The vast majority of our sample stated being unemployed, 106 (81.53%), whereas only 24 (18.46%) reported having a job. Mean age of our sample was 43.34 �� 8.11, mean years of education were 10.34 �� 3.02, and mean length of time on drug use was 26.07 �� 7.93 years and on methadone treatment 6.69 �� 4.18 years. In almost all subscales of the SCL-90R mean scores were >1 (Table 1). Highest mean score was observed in depressive dimension of the SCL-90R and selleck chemical lowest one in phobic anxiety (Table 1). Table 1 Mean scores on SCL-90R subscales and on AUDIT http://www.selleckchem.com/products/GDC-0449.html scale. Mean AUDIT score of our sampled population (6.91 �� 7.96) was higher than the Greek general population AUDIT score of 3.79 [56], a statistically significant difference of 3.12 (95% CI, 1.73 to 4.52, t(126) = 4.421, and P 15 indicating serious abuse/addiction. 3.9% scored in the range of 16�C19 indicating a high level of alcohol problems, and 8.7% scored >20 indicating possible dependence (Table 2). Table 2 Percentages of pathological values in SCL-90R and AUDIT. As to gender the female population of our sample scored significantly higher on anxiety, hostility, depression, phobic anxiety, and somatization. Females were also significantly younger than males (40.4 versus 44.3 P Quinapyramine to others without parental responsibilities. Lower levels for anxiety (1.19 versus 1.65, P