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Twelve, P?Casein kinase 2 �showed� �a similar� �but� �weaker� �correlation� �with a� �correlation� coefficient �of� �0�.�26� (P?see more biomarker �of the� �prostate�. �Disruption� �of the� �normal� anatomic prostatic �tissue� �results in� �an increase in� �serum� PSA. �This� �increase� �may result� �from� �malignant� �or� �benign� prostatic �diseases� �or� prostatic �manipulation� �including� catheterization.�24� �It is also� �known� �that� �patients� �with� �higher� PSA �and� �PV� �tend� �have a� �greater risk� �of� �urinary� �retention� find more �and thus�, catheterization.�25�, �26� �Although� �aging� �is related to� �a higher risk� �for� �urinary� �retention�,�27� �results from� �our� �study� �showed that� �there was no� �difference in� �age� �in terms of� indwelling catheter �use�. �In both� �groups�, �PV� �was� �significantly� �correlated� �with age� �and� PSA. �Both� �groups� �showed� �similar� coefficient �correlation� �values�. �Elevated� �serum� PSA �is observed� �in men� �with� BPH, prostatitis, �or� �prostate cancer�. �In� �another� �study� �conducted� �earlier� �in our� �center�, �from� �January� �1995� �to� �December� �2014�, �the overall� �prostate cancer� �detection� �rate� �was� �28�.7%. �With� �specific� �levels of� PSA �4�.0�C9.9?ng/mL �and� �10�.0�C19.9?ng/mL, �the� �prostate cancer� �detection� �rates� �were� �9�.3% �and� �13�.1%, �respectively�. �Meanwhile�, �the overall� �detection� �rate� �for� PSA �level� �4�.0�C20?ng/mL �was� �11�.3%, �which was� �similar to� �that� �reported� �in a� �study� �by� Shahab et?al.�28�, �29� �The� �indications� �for� �prostate� biopsy �in our� �center� �were� PSA > Some.0?ng/mL or even abnormal digital camera anal assessment (DRE)?findings.